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Abstract #1083

Quantification of carotid plaque compositon with Multi-contrast Atherosclerosis Characterization (MATCH) versus multisequence carotid MRI

Mohamed Kassem1,2, Ellen Boswijk2, Jochem Van der Pol2, Rik PM Moonen2, Jan Bucerius2, Zhaoyang Fan3, and M Eline Kooi1,2
1Radiology and Nuclear medicine, CARIM School for Cardiovascular Diseases, Maastricht, Netherlands, 2Radiology and Nuclear medicine, Maastricht university Medical Centre, Maastricht, Netherlands, 3Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, Los Angeles, CA, United States

Multisequence carotid MRI is commonly used to quantify plaque composition, but it has some disadvantages, i.e. long scan time and image mis-registration errors. Multi-contrast Atherosclerosis Characterization (MATCH) was developed to overcome these limitations. Eighteen patients with ≥2 mm carotid plaques underwent carotid multisequence and MATCH MRI. For the artery-based component detection, excellent agreement between MATCH and multisequence MRI was obtained for identification of LRNC, substantial for IPH and slight agreement for calcifications. No significant differences were shown in measurements of volume of LRNC, IPH, calcifications, percentage wall volume and normalized wall index.

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