Six patients with suspected cerebrospinal fluid leak but in whom no site of leakage had been identified and six controls underwent simultaneous, whole-body [18F]FDG PET/MRI imaging. Increased [18F]FDG uptake was found in paraspinal structures in all six patients and was significantly greater than in the corresponding areas of controls. Temporary but significant relief in symptoms resulted from blood patches placed at locations coinciding with PET/MRI abnormalities.
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