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Abstract #1152

Linking multi-joint biomechanics with cartilage composition from qMRI

Koren Roach1, Valentina Pedoia1, Jinhee J Lee1, Tijana Popovic1, Sharmila Majumdar1, and Richard B Souza1
1UCSF, San Francisco, CA, United States

Hip osteoarthritis is likely caused by changes in gait biomechanics and cartilage biochemistry and composition. In this study, we employed multivariate functional principal component analysis to identify gait waveform characteristics that were related to T and T2 relaxation times in the femoral and acetabular cartilage. Our results indicated that transverse and sagittal plane waveform characteristics are significantly related to T and T2 relaxation times in the femoral and acetabular cartilage and may be key planes of motion on which to focus preventative therapies for hip osteoarthritis.

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