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Abstract #1191

 Detection of radiation brain injury in patients with nasopharyngeal carcinoma: A comparative study of DTI, DKI and MAP-MRI

Weike Zeng1, Mengzhu Wang2, Yaxuan Pi3, Yi Li3, Xu Yan4, Guang Yang5, and Jun Shen6
1Deptpartment of Radiology, SUN YAT-SEN Memorial Hospital, SUN YAT-SEN University, Guangzhou, China, 2MR Scientific Marketing, Siemens Healthcare, Guangzhou, China, 3department of NEUROLOGY, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, 4MR Scientific Marketing, Siemens Healthineers, Shanghai, China, 5Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China, 6Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

Mean apparent propagator (MAP)-MRI, which builds a powerful analytical framework based on the random motion distribution of real water molecules, can more accurately and comprehensively characterize microstructure features of brain tissues than conventional diffusion imaging. This study investigated the application of MAP-MRI in the early diagnosis of radiation-induced brain injury in patients with nasopharyngeal carcinoma, compared with diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI).

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