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Abstract #1192

Trigeminal nerve tractography with accelerated simultaneous multislice readout-segmented echo planar diffusion tensor imaging

Yao Chia Shih1, Yeow Hoay Koh2, Soo Lee Lim1, Yen San Kiew1, Ee Wei Lim2, See Mui Ng1, Leon Qi Rong Ooi2, Wen Qi Tan1,3, Helmut Rumpel1, Eng King Tan2,3, and Ling Ling Chan1,3
1Department of Diagnostic Radiology, Singapore General Hospital, Singapore, Singapore, 2Department of Neurology, National Neuroscience Institute – Outram Campus, Singapore, Singapore, 3Duke-NUS Medical School, Singapore, Singapore

The impact of simultaneous multi-slice imaging (SMS) with short repetition time (TR) accelerated acquisition on diffusion tensor imaging (DTI) combined with readout-segmented echo planar imaging (RESOLVE) on the intra-cranial nerves is unexplored. Compared to non-SMS RESOLVE-DTI, two SMS RESOLVE-DTI protocols showed higher pontine signal-to-noise ratio (SNR). Consistent measures of different DTI metrics of cisternal trigeminal nerves across the three RESOLVE-DTI protocols and significant positive correlations of mean DTI metrics in pairwise comparison across these suggest that SMS RESOLVE-DTI allows fast and reliable evaluation of the microstructural integrity of the cisternal trigeminal nerve, with possible utility in trigeminal neuralgia.

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