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Abstract #1217

Implementing multi-echo balanced SSFP with a sequential phase-encoding order at 7T

Huilou Liang1,2, Ziyi Pan3, Chencan Qian1,2, Kaibao Sun1, Fanhua Guo1,2, Dehe Weng4, Jing An4, Yan Zhuo1,2,5, Hua Guo3, Danny J.J. Wang6, and Rong Xue1,2,7
1State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 2University of Chinese Academy of Sciences, Beijing, China, 3Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 4Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, 5CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing, China, 6Laboratory of FMRI Technology (LOFT), Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States, 7Beijing Institute for Brain Disorders, Beijing, China

In the past decade, passband bSSFP has emerged as an alternative method to the widely-used GE-EPI in fMRI studies at high-fields. Multiline bSSFP with an interleaved phase-encoding order was further proposed to accelerate bSSFP fMRI. However, it intrinsically suffers from high spatial frequency ghosts which blur the image. In this study, we developed a multi-echo bSSFP sequence using a sequential phase-encoding order, combined with the GRAPPA technique for ghost elimination. In vivo experiments demonstrated that this sequence could shorten the imaging time and provide high-quality structural and functional MR images of the human brain at 7T with sub-millimeter resolution.

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