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Abstract #1218

Feasibility of high spatial and temporal resolution multi-echo multi-band whole brain resting-state functional MRI on a compact 3T system

Daehun Kang1, Hang Joon Jo1,2, Myung-Ho In1, Erin Gray1, Ek T Tan3,4, Thomas K Foo4, Uten Yarach1, Nolan K Meyer1, Joshua D Trzasko1, John Huston1, Matt A Bernstein1, and Yunhong Shu1
1Mayo Clinic, Rochester, MN, United States, 2Hanyang University, Seoul, Republic of Korea, 3Hospital of Special Surgery, New York, NY, United States, 4GE Global Research, Niskayuna, NY, United States

Multi-echo fMRI has been shown to provide better denoising and result in improved functional analysis compared to single-echo acquisition, but it reduces the temporal resolution and inhibits high-resolution imaging. Multi-band imaging and in-plane acceleration can compensate for the reduced resolution. The high performance gradient on a compact 3T scanner can further reduce the echo-spacing and accelerate the acquisition. Here we demonstrate that high spatial-resolution ME-MB fMRI is achievable with high temporal resolution on the compact 3T. The effectiveness of ME acquisition is evaluated with different artifact reduction strategies in whole brain resting-state fMRI and compared with the standard SE acquisition.

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