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Abstract #1223

Real-Time Respiration Compensation in Oscillating Steady State fMRI

Amos A Cao1 and Douglas Noll2
1University of Michigan, Ann Arbor, MI, United States, 2Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Oscillating Steady-State Imaging (OSSI) is a new steady-state sequence for high-SNR fMRI. Respiration-induced B0 changes cause undesirable changes to the OSSI steady-state, resulting in signal artifacts. To address this problem, we present a prospective correction method which utilizes a self-navigating spiral trajectory to measure and correct for B0 changes in real-time. In an initial fMRI proof-of-concept, our real-time correction method increased the number of activated voxels by 454% and increased mean tSNR by 81%. Real-time prospective correction has the potential to outperform retrospective correction methods by directly reducing perturbations to steady-state magnetization during acquisition.

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