Abstract #1226

Modelling the Laminar VASO Signal Change in Human V1 at 7T

Atena Akbari¹, Saskia Bollmann¹, Tonima S Ali ¹, and Markus Barth^1,2,3

¹Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ²ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, Brisbane, Australia, ³School of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia

In this study, we used the “cortical vascular model” for human V1 at 7T to simulate the laminar VAscular-Space-Occupancy (VASO) signal change. For comparison, we conducted VASO experiments on a group of healthy subjects to measure laminar signal change in V1. Results show a very good agreement between the model prediction and the experimental results once the volume changes of the different vascular compartments (arterioles, capillaries, venules) are taken into account.

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