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Abstract #1320

REACT-MD: simultaneous non-contrast-enhanced subclavian MRA and fat suppressed direct thrombus imaging (MPRAGE) with a large field-of-view

Masami Yoneyama1, Shuo Zhang2, Yasuhiro Goto3, Michinobu Nagao4, Kayoko Abe4, Osamu Togao5, Isao Shiina3, Kazuo Kodaira3, Yutaka Hamatani3, and Marc Van Cauteren6
1Philips Japan, Tokyo, Japan, 2Philips Healthcare, Hamburg, Germany, 3Department of Radiological Services,, Tokyo Women’s Medical University, Tokyo, Japan, 4Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan, 5Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 6Philips Healthcare, Best, Netherlands

Direct visualization of the plaques and vessel wall lesions in addition to luminal changes is of clinical importance for management of patients with atherosclerotic disease. In this work, the recently proposed REACT (Relaxation-Enhanced Angiography without Contrast and Triggering) technique was further developed and particularly optimized with Multiple Delays (REACT-MD) to simultaneously provide non-contrast-enhanced MR angiogram and MPRAGE (magnetization prepared rapid gradient echo) type images with uniform background tissue suppression over a large field of view. Initial results in patients showed great promise in detection of luminal changes and plaques for assessment of systemic atherosclerosis in one single scan.

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