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Abstract #1325

Highly accelerated vessel wall imaging using CAIPIRINHA accelerated SPACE and IFR-CS

Sen Jia1,2, Zhilang Qiu1,2, Lei Zhang2, Xin Liu2, Hairong Zheng2, and Dong Liang2
1University of Chinese Academy of Sciences, Shenzhen, China, 2Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Joint intracranial and carotid 3D vessel wall imaging (VWI) with an isotropic spatial resolution between 0.5-0.6 mm is promising in diagnosing arterial wall diseases but leads to clinically impractical scan time. CAIPIRINHA 3x3 undersampling with elliptical scanning is used to expedite the VWI by 11-fold without less sampling the high-frequency region of k-space. Iterative L1-ESPIRiT algorithm is employed for reconstruction with GRAPPA result as the initialization. The scheme of Iterative Feature Refinement is embedded into L1-ESPIRiT iteration to avoid potential over-smoothing issue. Finally, the 3D 11x VWI scan at an isotropic resolution of 0.6 mm takes only 3.5 minutes.

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