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Abstract #1326

iSNAP sequence for simultaneous measurement of whole brain dynamic MRA, MRA, intracranial vessel wall and T1W structural brain MRI

Zhensen Chen1, Zechen Zhou2, Niranjan Balu1, Haikun Qi3, Baocheng Chu1, Thomas S Hatsukami4, and Chun Yuan1
1Vascular Imaging Lab and BioMolecular Imaging Center, Radiology, University of Washington, Seattle, WA, United States, 2Philips Research North America, Cambridge, MA, United States, 3Biomedical Engineering, King's College London, London, United Kingdom, 4Surgery, University of Washington, Seattle, WA, United States

In this study, a whole brain sequence named iSNAP, with 0.8 mm isotropic voxel size and 6 min 30 sec acquisition time, was developed to simultaneously obtain four different image contrasts (dynamic MRA [dMRA] for blood flow monitoring, MRA for luminal stenosis measurement, black blood image for vessel wall [VW] measurement and T1W for brain structural imaging). Preliminary testing results on a healthy volunteer and two patients with cerebrovascular diseases demonstrated the feasibility and potential of the sequence.

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