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Abstract #1329

Time-resolved 3D Flow-MRF for relaxation and velocity quantification in the carotid arteries

Lisa Leroi1, Sebastian Flassbeck2,3, and Sebastian Schmitter1,2
1Physikalisch-Technische Bundesanstalt Berlin (PTB), Braunschweig and Berlin, Germany, 2Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 3Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany

The simultaneous quantification of blood velocity and tissue relaxation times could be a valuable tool for clinicians, especially in the carotid arteries, where atheroma plaques could occur. This can be achieved using the recently presented Flow-MRF technique that relies on the acquisition of randomly distributed gradients m1 momentum using a FISP MRF-sequence, with varying flip angle and fixed TR. In this work, Flow-MRF is extended to a time-resolved 3D acquisition and successfully applied in-vivo to the carotid bifurcation at 3T. T1, T2 and 3D time-resolved flow maps are recovered in a 3D slab.

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