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Abstract #1349

Ultrafast functional MRI signals reflect activation sequence in the mouse visual pathway

Rita Gil1, Francisca F. Fernandes1, and Noam Shemesh1
1Champalimaud Neuroscience Programme, Champalimaud Centre for the Unknown, Lisbon, Portugal

We investigated BOLD response profiles along the entire mouse visual pathway (with monocular stimulation) using an ultrafast fMRI acquisition with 50 ms temporal resolution and quantified onset, half-maximum and peak times. To achieve the spatial coverage with this temporal resolution, an oblique slice covering the entire visual pathway was tailored. The quantified onset times were the only parameter correlating with the visual pathway neural input order. Our findings highlight a potential importance for onset time quantification – requiring ultrafast fMRI acquisitions – as a signature capable of mapping the underlying activation sequence of events in distributed neural networks.

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