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Abstract #1419

Detection of multiple sclerosis lesion with T1 and T2* MR Fingerprinting

Ingo Hermann1,2, Ralf Schmidt1, Benedikt Rieger1, Eloy Martinez-Heras3, Elisabeth Solona3, Sara Llufriu3, Achim Gass4, Lothar R. Schad1, and Frank G. Zöllner1
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany, 2Magnetic Resonance Systems Lab, Department of Imaging Physics, Delft University of Technology, Delft, Netherlands, 3Center of Neuroimmunology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Universitat de Barcelona, Barcelona, Spain, 4Department of Neurology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany

We evaluated an MRF-EPI sequence for simultaneous T1 and T2* quantification in 44 patients with multiple sclerosis (MS) lesions at two scanners. We found significantly increased T1 and T2* times in MS lesions with differences up to 100 %. MS lesions resulted in broad distribution in the T1, T2* space compared with dense, separated clusters for white and gray matter.

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