Myelin water imaging allows the assessment of relative myelination by estimating the myelin water fraction (MWF). This work investigated if the degree of MWF loss in multiple sclerosis is associated with T1 hypointense and isointense lesions. Within n = 1668 FLAIR lesions of n = 63 MS patients, 79% had a hypointense correlate, and 21% of the lesions had an isointense appearance on non-enhanced T1-weighted images. Significant differences were found for hypointense (MWFmean = 0.126) and isointense (MWFmean = 0.185) lesions. These results show varying degrees of myelin reduction.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords