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Abstract #1484

Age and location related hemodynamic changes in the carotid artery of healthy adults assessed by 4D flow MRI

Guiling Zhang1 and Wenzhen Zhu1
1Tongji hospital, Wuhan, China

Atherosclerosis is the predominant risk factor of ischemic stroke. Age and location are intrinsic factors in the development of carotid artery plaque. Therefore, the relationship between hemodynamic changes and location/age in healthy subjects can help understand how the hemodynamic states influence carotid incidents. Our study found velocity/WSS/PG decreased with age. And proximal ICA, the most common point arising atherosclerotic plaque, displayed the lowest velocity/WSS/PG. It may imply this state of hemodynamics are more likely to cause atherosclerotic plaques. The multi-parameter analysis of 4D flow MRI may offer suggestions for choosing age and location matched control cohorts in future study.

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