Abstract #1524

Multi-modality evaluation of Hyposmia in patients with Parkinson’s disease and atypical Parkinsonism

A Ankeeta¹, Shefali Chaudhary¹, S Senthil Kumaran¹, Priyanka Bhat², and Vinay Goyal²

¹NMR and MRI facility, All India Institute of Medical Sciences, New Delhi, India, ²Neurology, All India Institute of Medical Sciences, New Delhi, India

The pattern of Hyposmia hemodynamic response, functional connectivity and ERP response was investigated in patients with Parkinson's disease, Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP). Results revealed the presence of significant olfactory loss correlated with differential pattern in the olfactory pathway including frontal region and temporal areas. MRI, BOLD and EEG, can be used to detect early biomarker(s) for the identification of Parkinson and atypical Parkinsonism patients on the basis of hyposmia.

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