Meeting Banner
Abstract #1544

Investigation of amide proton transfer imaging in Multiple system atrophy at 3.0 Tesla

Na Lu1,2, Shuhua Li3, Chunmei Li1, Pu-Yeh Wu4, Wen Su3, Haibo Chen3, Piu Chan3, and Min Chen1,2
1Department of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China, 2Graduate School of Peking Union Medical College, Beijing, China, 3Department of Neurology, Beijing Hospital, National Center of Gerontology, Beijing, China, 4GE Healthcare, MR Research China, Beijing, China

Multiple system atrophy (MSA) is in great need of diagnosis in its early stage. Our study aims to evaluate the feasibility of using amide proton transfer (APT) imaging in detection of multiple system atrophy (MSA) at 3.0 Tesla. We found that APT MTRasym values were significantly higher in MSA patients than in normal controls at red nucleus, substantia nigra, thalamus and putamen. We also found that APT MTRasym values were significantly higher in probable MSA than in possible MSA patients at red nucleus, caudate and putamen. Hence, CEST may be valuable in diagnosing and predicting the progression of MSA.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here