Yu Tang1, Maohua Wang2, Ting Zheng1, Fengying Yuan1, Fugang Han1, and Guangxiang Chen1
1Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou, China, 2Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, China
In recent decades, a growing
number of structural neuroimaging studies
of grey matter (GM) in trigeminal neuralgia (TN) have reported inconsistent
alterations. We carried out
a systematic
review and meta-analysis to identify consistent and replicable GM
volume abnormalities in TN patients. Our findings provide a
thorough profile of GM volume alterations in TN patients and
constitute robust evidence that aberrant GM volumes in the brain regions
regulating and moderating sensory-motor and affective processing may play an
important role in the pathophysiology of TN.
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