Abstract #1593

Association between Morphologies of Middle Cerebral Artery Occlusion on Vessel Wall Imaging and Cerebrovascular Events in Moyamoya Patients

Fang Wu¹, Cong Han², Zhaoyang Fan³, and Qi Yang⁴

¹Radiology, Xuanwu hospital, Capital Medical University, Beijing, China, ²Department of Neurosurgery, 307 Hospital of Chinese People's Liberation Army, Beijing, China, ³Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, ⁴Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China

In this study, we used whole-brain vessel wall imaging (VWI) to characterize morphologies of middle cerebral artery (MCA) occlusion in patients with MMD, and explore their relationship to clinical findings. We found that plugged MCA was associated with ischemic stroke, however, vanishing MCA correlated with intraventricular hemorrhage. We also found that hemispheres with vanishing MCA manifested a higher degree of lenticulostriate artery (LSA) dilation and proliferation. The results suggest that there are two types of MCA occlusion in MMD, correlating with different stroke types and extent of perforator proliferation. Morphological analysis of occluded MCA using VWI may help understand the stroke mechanism of MMD.

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