Abstract #1597

Optimized T1-weighted dark blood CS-SPACE - assessment of superficial extracranial arteries

Konstanze Viktoria Anna Valerie Guggenberger¹, Patrick Vogel¹, Nils Venhoff², Ute Ludwig³, Marc Schmalzing⁴, Esther Raithel⁵, Axel Joachim Krafft³, Thomas Ness⁶, Jost Hillenkamp⁷, Horst Urbach⁸, Stephan Meckel⁸, and Thorsten Bley¹

¹Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Wuerzburg, Germany, ²Clinic for Rheumatology and Clinical Immunology, University Hospital Freiburg, Freiburg, Germany, ³Department of Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany, ⁴Rheumatology/Clinical Immunology Department, Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany, ⁵Siemens Healthcare, Erlangen, Germany, ⁶University Eye Center, University Hospital Freiburg, Freiburg, Germany, ⁷Department of Ophthalmology, University Hospital Wuerzburg, Wuerzburg, Germany, ⁸Department of Neuroradiology, University Hospital Freiburg, Freiburg, Germany

Superficial extracranial arteries are predilection sites for disease manifestation in large vessel vasculitides. We evaluated the suitability of a whole-brain T1-weighted dark blood CS-SPACE sequence, initially developed for intracranial vessel wall imaging, for visualization of vasculitic changes of superficial extracranial arteries. 53 patients were analyzed in a prospective blinded two university medical center trial. First clinical results demonstrate the technique`s applicability for clinical application. Mural thickening and contrast-enhancement of superficial extracranial arteries are clearly visible. The optimized VWI protocol offers potential for assessment of intra- and extracranial disease extent in case of suspected large vessel vasculitis in one single examination.

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