The extent of intracranial large artery involvement and its assessment is still part of on-going research. Our study group has developed a whole-brain T1-weighted dark blood CS-SPACE sequence suitable for intracranial vessel wall imaging in large-artery vasculitis combined with a dedicated post-processing tool. 53 patients were analyzed in a prospective blinded two university medical center trial. First clinical results demonstrate the technique`s suitability for clinical application. Mural thickening and contrast-enhancement as well as luminal changes are readily visible. However, certain confounders, especially atherosclerotic vessel wall lesions as well as vasa vasorum still propose major challenges for diagnosing intradural vasculitic affection.