This study aimed to investigate if zero-echo-time arterial-spin-labeling (ZTE ASL) MRA is feasible in the diagnosis of intracranial artery stenosis(ICAD). 25 patients with confirmed clinically stroke or transient ischemic attacks were recruited. For these patients, the correspondingly acquired ZTE-MRA images were compared with those using TOF-MRA technique. DSA imaging was also applied for and considered as a reference standard. For large-medium-sized intracranial arterial segments, ZTE-MRA showed better performance in the image quality and diseased artery detection than TOF-MRA. Therefore, ZTE-MRA can be considered as a promising technique to be further applied in the clinic routinely for patients with ICAD.
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