Abstract #1644

Characterization of biomechanical properties of cerebral vessels using magnetic resonance elastography

Shengyuan Ma¹, Linjie Wang², Mo Zhu², Yanle Hu³, Yiping Du¹, Joel R. Garbow⁴, Curtis Johnson⁵, Chun-hong Hu², and Yuan Feng¹

¹Shanghai Jiao Tong University, Shanghai, China, ²Department of Radiology, The first affiliated hospital of Soochow University, Suzhou, China, ³Mayo Clinic, Phoenix, AZ, United States, ⁴Washington University in St. Louis, St. Louis, MO, United States, ⁵University of Delaware, Newark, DE, United States

Measurements of the biomechanical properties of the cerebral vessels could help diagnosis and prognosis of diseases such as lacunar infarction. In this study, shear moduli of the cerebral vessels were measured using both magnetic resonance elastography (MRE) and MR Angiography (MRA). The magnitude images from MRE were registered to MRA images to obtain the shear moduli of the cerebral vessels. Results showed significant correlations between age and gender in terms of the storage modulus. Significant differences between lacunar infarction and healthy control group were also observed in terms of the absolution shear modulus.

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