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Abstract #1649

MRI features of cerebral small vessel disease in patients with systemic lupus erythematosus

Yiwei Che1, Yanwei Miao1, Yuhan Jiang1, Peipei Chang1, and Lizhi Xie 2
1Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Department of Radiology, GE healthcare, Beijing, China

Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease, which can involve the nervous system, and cerebrovascular damage is the most common. Yet, the relationship between SLE and Cerebral small vessel disease (CSVD) are still not clear. The following study evaluated the MRI findings of enlarged perivascular space (EPVS), white matter hyperintense (WMH) and lacunes of CSVD in patients with SLE. The results showed that CVSD in SLE group was more serious than healthy normal control group, and complement C3 and disease duration were the influencing factors on the development of CSVD in SLE patients.

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