The proximal internal carotid artery (pICA) stenosis is an important cause of ischemic cerebrovascular disease. We evaluated the predicting power to identify unilateral pICA stenosis based on the intracranial 3D time of flight MR angiography (MRA) with multi-slab acquisition used in daily clinical practice by a quantitative assessment of the asymmetry in the middle cerebral artery (MCA). The result revealed that the MCA volume ratio of subjects were significantly lower than controls and the accuracy, sensitivity and specificity to identify subjects were 0.71, 0.71 and 0.88. The quantitative evaluation on intracranial MRA may provide additional information to unilateral pICA stenosis.
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