We developed and validated a convolutional neural network for the fully automated 3D segmentation of the cerebral vasculature from 4D flow MRI for rapid flow analysis. Using 53 4D flow MRI scans, including 16 patients with intracranial atherosclerotic disease, we trained and tested our CNN using 10-fold cross validation. We assessed net flow and peak velocities across all of the major arteries and veins of the intracranial vasulature between automated and manually performed analysis. Across all metrics and regions, we found the automated segmentation showed excellent agreement with the manual, while taking a fraction of the time to perform.
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