The goal of this study is to investigate whether choroid plexus (CP) activity, quantified as perfusion measured from arterial spin labeling, is altered in patients with cerebrovascular disease. Cohorts comprised arterial intracranial stenosis (n=56), sickle cell disease (n=41), and healthy controls (n=31). In controls and stenosis patients, CP and gray matter perfusion were similar; in patients with sickle cell disease, CP-to-gray matter perfusion was reduced (p<0.001) relative to other cohorts. This finding is discussed in the context of how efficient CSF perivascular flow surrounding dilated arterial spaces may require reduced CSF production activity to subserve waste clearance.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords