We studied the changes in rCBV
introduced by echo-planar imaging (EPI) distortion correction methods when
applied to EPI dynamic susceptibility contrast (DSC)-MRI. The results obtained
using FSL TOPUP and EPIC distortion correction methods indicate that both
subcortical and cortical regions are affected and returning an overall increase
in rCBV. In the context of longitudinal EPI-based analysis in glioblastoma
patients, EPI distortions and subsequent corrections are important determiners for
assessing robust responses of rCBV change.