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Abstract #1711

Simultaneous Fast and Slow DCE: temporal multiresolution and spatial high resolution T1 dynamics of the whole brain from a single continuous scan

Ingomar Gutmann1, Julia Furtner2, Gregor Kasprian2, Gerhard Krexner3, Daniela Prayer2, and Patrick Thurner2
1University of Vienna, Vienna, Austria, 2Medical University Vienna, Vienna, Austria, 3University of Vienna, Wien, Austria

We present DCE acquisition with high spatial resolution that excels the guidelines of the ACR for spatial resolution, maintaining whole brain coverage at all times, while at the same time providing a temporal sampling rate of fast enough to make accurate flow and permeability measurements from T1-weighted DCE MRI in a clinical neuro-oncology setting possible.Furthermore we demonstrate the use of radial spoke aggregation in GRASP reconstruction for DCE perfusion imaging of the brain and show preliminary results on the impact of variable temporal resolution on estimating pharmacokinetic models.

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