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Abstract #1723

Experience counts! Comparison of ROI placement strategies for radiomics analysis of gliomas

Bárbara Schmitz Abecassis1,2, Koji Sakai2, Tomonori Toyotsuji2, Yoshiaki Ota2,3, and Kei Yamada2
1Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, 3Department of Radiology, University of Michigan, Ann Arbor, MI, United States

Glioma delineation is complex and time-consuming. We evaluated whether a technically less challenging method could potentially bypass this tedious process, when using a simple manual circular-ROI by less trained personnel. We assessed whether applying a circular-ROI to clinical 3T-MRIs from 12 glioma patients, would extract significantly different GLI features. We compared it to the gold-standard manual delineation approach, having 3 observers with different levels of expertise placing the ROIs. Experience matters to extract consistent GLI features across delineation runs. The different ROI methods extracted significantly different GLI features, emphasizing the importance of delineation strategies when analyzing heterogeneous tumors like gliomas.

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