A major barrier of clinical application of 3D T1 sequence is the long acquisition time. Compressed SENSE (CS-SENSE) was introduced into the clinical routine and showed reduced scan time without reduced image quality. However, automatically quantitative assessment of brain structure has not been certificated up to date. This study evaluated the different acceleration factors of CS-SENSE or SENSE of a 3D brain T1 sequence with qualitative and quantitative measurements in health volunteers and patients, in order to assess the feasibility of 3D brain structural imaging acceleration.
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