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Abstract #1755

Intraplatform Repeatability and Interplatform Agreement of Whole-Brain 3D MRE

Yuxiang Zhou1, Yuan Le2, Kevin J Glaser2, Jun Chen2, Roger C Grimm2, Arvin Arani2, Bradley D Bolster, Jr3, Stephan Kannengiesser4, John Huston III2, Joel P Felmlee2, Richard L Ehman2, and Joseph M Hoxworth1
1Radiology, Mayo Clinic, Phoenix, AZ, United States, 2Radiology, Mayo Clinic, Rochester, MN, United States, 3Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States, 4Siemens Healthcare GmbH, Erlangen, Germany

Using MRE to evaluate the brain requires acquisition of the full 3D wave field and application of 3D inversion processing to generate valid stiffness maps. The goal of this study was to assess the precision and cross-platform reproducibility of whole brain stiffness measurements obtained with prototype 3D SE-EPI-based MRE techniques, as implemented on GE and Siemens MRI platforms, with the goal of standardization. Our data showed excellent intraplatform repeatability and good interplatform agreement.

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