Abstract #1755

Intraplatform Repeatability and Interplatform Agreement of Whole-Brain 3D MRE

Yuxiang Zhou¹, Yuan Le², Kevin J Glaser², Jun Chen², Roger C Grimm², Arvin Arani², Bradley D Bolster, Jr³, Stephan Kannengiesser⁴, John Huston III², Joel P Felmlee², Richard L Ehman², and Joseph M Hoxworth¹

¹Radiology, Mayo Clinic, Phoenix, AZ, United States, ²Radiology, Mayo Clinic, Rochester, MN, United States, ³Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States, ⁴Siemens Healthcare GmbH, Erlangen, Germany

Using MRE to evaluate the brain requires acquisition of the full 3D wave field and application of 3D inversion processing to generate valid stiffness maps. The goal of this study was to assess the precision and cross-platform reproducibility of whole brain stiffness measurements obtained with prototype 3D SE-EPI-based MRE techniques, as implemented on GE and Siemens MRI platforms, with the goal of standardization. Our data showed excellent intraplatform repeatability and good interplatform agreement.

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