Abstract #1770

Can 7T MPRAGE match MP2RAGE for gray-white matter contrast?

Ícaro A F de Oliveira^1,2, Thomas Roos¹, Serge O Dumoulin^1,2,3, and Wietske van der Zwaag¹

¹Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, ²Experimental and Applied Psychology, VU University, Amsterdam, Netherlands, ³Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, Netherlands

We compared MPRAGE and MP2RAGE at Ultra-High Field (UHF) in terms of signal separability in gray and white matter. Using a k-space shutter, kt-point universal pulses for signal excitation, and an efficient TR-FOCI for signal inversion, we obtained very good signal contrast throughout the brain, including the cerebellum, for the MPRAGE. Nevertheless, gray-white matter contrast was larger in the MP2RAGE data, leading to better segmentation results, especially in areas affected by low B1+. Hence, MP2RAGE appears more suitable for 7T T1-weighted anatomical data, despite the longer acquisition times.

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