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Abstract #1770

Can 7T MPRAGE match MP2RAGE for gray-white matter contrast?

Ícaro A F de Oliveira1,2, Thomas Roos1, Serge O Dumoulin1,2,3, and Wietske van der Zwaag1
1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 2Experimental and Applied Psychology, VU University, Amsterdam, Netherlands, 3Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, Netherlands

We compared MPRAGE and MP2RAGE at Ultra-High Field (UHF) in terms of signal separability in gray and white matter. Using a k-space shutter, kt-point universal pulses for signal excitation, and an efficient TR-FOCI for signal inversion, we obtained very good signal contrast throughout the brain, including the cerebellum, for the MPRAGE. Nevertheless, gray-white matter contrast was larger in the MP2RAGE data, leading to better segmentation results, especially in areas affected by low B1+. Hence, MP2RAGE appears more suitable for 7T T1-weighted anatomical data, despite the longer acquisition times.

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