Abstract #1771

Improved combination of multi-inversion time images for fluid and white matter suppression

Dzung L Pham¹, Neville Gai², Yi-Yu Chou³, Abbey Goodyear², Wen-Tung Wang³, and John A. Butman²

¹Center for Neuroscience and Regenerative Medicine, Henry M. Jackson Foundation, Bethesda, MD, United States, ²National Institutes of Health, Bethesda, MD, United States, ³Henry M. Jackson Foundation, Bethesda, MD, United States

Fluid and White Matter Suppression (FLAWS) MRI uses two inversion times within a T1-weighted magnetization-prepared gradient echo sequence to enhance visualization of gray matter structures within the brain. FLAWS is based on the MP2RAGE sequence, but with different inversion times, followed by a voxel-wise minimum. In this work, we demonstrate that a variation of the regularized, ratio combination approach of MP2RAGE yields superior gray matter contrast-to-noise and intensity uniformity compared to the originally proposed FLAWS MRI combination based on minimum intensity.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.