Fluid and White Matter Suppression (FLAWS) MRI uses two inversion times within a T1-weighted magnetization-prepared gradient echo sequence to enhance visualization of gray matter structures within the brain. FLAWS is based on the MP2RAGE sequence, but with different inversion times, followed by a voxel-wise minimum. In this work, we demonstrate that a variation of the regularized, ratio combination approach of MP2RAGE yields superior gray matter contrast-to-noise and intensity uniformity compared to the originally proposed FLAWS MRI combination based on minimum intensity.
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