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Abstract #1800

Ultrashort-T2* component differences in white matter regions of the brain

Nikhil Deveshwar1 and Peder E. Z. Larson1
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

This work presents a study detailing how ultrashort-T2* measurements can provide new and complimentary characterizations and differentiations of white matter anatomy in comparison to classic DTI measurements. Specifically the magnitude and frequency shift components of the measured signal are significantly different between white matter with thick versus thin myelin sheaths and provides new methods of assessing myelin content in white matter when compared to FA, MD, and V1 values. These results show that this method could be used to better characterize and study demyelinating diseases such as multiple sclerosis.

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