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Abstract #1810

Improved Cerebral Microbleed vs Calcification Discrimination using QSM compared to SWI Phase Maps

Salil Soman1, Kyuwon Lee2, Magdy Selim3, Aristotelis Filippidis4, Ajit Thomas4, Pascal Spincemaille5, and Yi Wang5
1Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, 2Radiology, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, 3Neurology, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, 4Neurosurgery, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, 5Radiology, Weill Cornell Medicine, New York, NY, United States

Cerebral microbleeds are bleeds < 1 cm seen on MRI, not visible on CT, which play a role in diagnosing disease and identifying risks of developing multiple diseases. Many susceptibility based techniques, such as SWI require a phase map to distinguish CMB from calcification. However, studies have demonstrated that for non-CMB bleeds on GRE and SWI, the phase dominant sign may differ across slices, preventing clinical interpretation. We compared the dominant sign for candidate CMBs on SWI phase maps and MEDI QSM images, and found that QSM images showed much less change in dominant sign than SWI phase maps.

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