Abstract #1810

Improved Cerebral Microbleed vs Calcification Discrimination using QSM compared to SWI Phase Maps

Salil Soman¹, Kyuwon Lee², Magdy Selim³, Aristotelis Filippidis⁴, Ajit Thomas⁴, Pascal Spincemaille⁵, and Yi Wang⁵

¹Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, ²Radiology, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, ³Neurology, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, ⁴Neurosurgery, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States, ⁵Radiology, Weill Cornell Medicine, New York, NY, United States

Cerebral microbleeds are bleeds < 1 cm seen on MRI, not visible on CT, which play a role in diagnosing disease and identifying risks of developing multiple diseases. Many susceptibility based techniques, such as SWI require a phase map to distinguish CMB from calcification. However, studies have demonstrated that for non-CMB bleeds on GRE and SWI, the phase dominant sign may differ across slices, preventing clinical interpretation. We compared the dominant sign for candidate CMBs on SWI phase maps and MEDI QSM images, and found that QSM images showed much less change in dominant sign than SWI phase maps.

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