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Abstract #1815

Quantitative susceptibility mapping reveals increased iron content of subcortical nuclei in hypertensive patients

Xin Li1, Yue Qin1, Shaoyu Wang2, Xiang Feng3, Yifan Qian1, Juan Tian1, Liyao Liu1, Yinhu Zhu1, Boyuan Jiang1, and Yanqiang Qiao1
1XI’AN DAXING HOSPITAL, ShaanXi, Xi’an, China, 2Siemens Healthcare Ltd., ShaanXi, Xi’an, China, 3Siemens Healthcare Ltd., Beijing, China

Hypertension is known to be a major risk factor for damage to target organs, including the brain. Hypertension may be associated with increased heme content and non-heme iron contents. QSM is a potent imaging method that can provide a noninvasive and accurate measurement of iron content in the brain for diagnosing diseases and monitoring progression and treatment. This study evaluated the feasibility of QSM in the measurement of brain iron deposition in patients with hypertension. We found increased iron accumulation primarily in the deep gray matter nucleus in hypertensive patients.

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