Abstract #1814

Highly Accelerated Wave-CAIPI Post-Contrast 3D-T1 Compared to Standard Post-Contrast 3D-T1 SPACE for Detection of Abnormal Enhancing Lesions.

Augusto Lio Mota Goncalves Filho^1,2, Maria Gabriela Figueiro Longo^1,2, John Conklin^1,2, Stephen Cauley^1,2, Daniel Polak³, Wei Liu⁴, John Kirsch^1,2, Kawin Setsompop^1,2, Ramon Gilberto Gonzalez¹, Pamela Schaefer¹, Susie Yi Huang^1,2,5, and Otto Rapalino¹

¹Radiology, Massachusetts General Hospital, Boston, MA, United States, ²Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ³Siemens Healthineers, Erlangen, Germany, ⁴Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ⁵Harvard Medical School, Boston, MA, United States

We present the first large-scale evaluation of the diagnostic performance and image quality of highly accelerated Wave-CAIPI post-contrast 3D-T1 SPACE (Wave-T1 SPACE) compared to standard post-contrast 3D-T1 SPACE for the detection of intracranial enhancing lesions in patients undergoing 3T MRI scanning. Two neuroradiologists assessed the images in a head-to-head comparison, and found no significant difference between the two sequences for detection of abnormal intracranial enhancement and overall diagnostic quality, despite a nearly 3-fold decrease in acquisition time of post-contrast Wave-T1 SPACE. The application of highly-accelerated 3D imaging may improve use of MRI resources while reducing motion artifacts and patient anxiety.

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