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Abstract #1814

Highly Accelerated Wave-CAIPI Post-Contrast 3D-T1 Compared to Standard Post-Contrast 3D-T1 SPACE for Detection of Abnormal Enhancing Lesions.

Augusto Lio Mota Goncalves Filho1,2, Maria Gabriela Figueiro Longo1,2, John Conklin1,2, Stephen Cauley1,2, Daniel Polak3, Wei Liu4, John Kirsch1,2, Kawin Setsompop1,2, Ramon Gilberto Gonzalez1, Pamela Schaefer1, Susie Yi Huang1,2,5, and Otto Rapalino1
1Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Siemens Healthineers, Erlangen, Germany, 4Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 5Harvard Medical School, Boston, MA, United States

We present the first large-scale evaluation of the diagnostic performance and image quality of highly accelerated Wave-CAIPI post-contrast 3D-T1 SPACE (Wave-T1 SPACE) compared to standard post-contrast 3D-T1 SPACE for the detection of intracranial enhancing lesions in patients undergoing 3T MRI scanning. Two neuroradiologists assessed the images in a head-to-head comparison, and found no significant difference between the two sequences for detection of abnormal intracranial enhancement and overall diagnostic quality, despite a nearly 3-fold decrease in acquisition time of post-contrast Wave-T1 SPACE. The application of highly-accelerated 3D imaging may improve use of MRI resources while reducing motion artifacts and patient anxiety.

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