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Abstract #1822

Multimodal quantitative magnetic resonance neurography in chronic inflammatory demyelinating polyneuropathy

Su Xiaoyun1, Zheng Chuansheng1, Kong Xiangquan1, Lu Zuneng2, Osamah Alwalid1, and Zhang Huiting3
1Radiology, union hospital, tongji medical college, Huazhong University of science and technology, Wuhan, China, 2Neurology, Renming Hospital of Wuhan University,, Wuhan, China, 3MR Scientific Marketing, Siemens Healthcare, Shanghai, China

Conventional imaging is insufficient for diagnosis and management of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Brachial and lumbosacral plexus of 37 CIDP patients and 37 age and gender-matched controls were examined by using multi-sequences. Our study showed that fractional anisotropy (FA) had the most sensitivity, while contrast-enhanced ratio (CR) had the most specificity in single-parameter. The combination of FA and CR value had the best diagnostic efficiency. FA had a negative correlation with course duration, and CR positive correlation with CSF protein. SPACE combined with DTI and contrast enhancement sequences serve as a recommended composite protocol.

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