Abstract #1823

Detection of microstructural abnormalities of gray matter in migraineurs without aura using Mean Apparent Propagator (MAP) MRI model

Su Xiaoyun¹, Wang Jing¹, Chi Bin¹, Zhu Qing², Zhang Huiting³, Zhang Xiaoyong⁴, and Zheng Chuansheng¹

¹Radiology, union hospital, tongji medical college, Huazhong University of science and technology, Wuhan, China, ²Neurology, union hospital, tongji medical college, Huazhong University of science and technology, Wuhan, China, ³MR Scientific Marketing, Siemens Healthcare, Shanghai, China, ⁴Shanghai Key Laboratory of Magnetic Resonance,East China Normal University, Shanghai, China

The mean apparent propagator (MAP) MRI is an advanced diffusion model proposed recently for brain microstructure imaging. In this study, the MAP-MRI model was applied in diagnosis of migraineurs patient without aura. The results found that the parameter of MAP-MRI showed significant differences in in superior frontal gyrus, temporal lobe, cingulate gyrus, parahippocampal gyrus, hippocampus and left amygdata in MWoAs between patients and healthy controls. These findings further suggest involvement of the gray matter in pathology of migraine without aura.

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