This study aimed to quantitative measurement of cerebral blood flow in different brain regions of different levels of blood pressure by mTI ASL. In the first part of this study, we evaluated the reproducibility of mTI-ASL in healthy subjects, and then mTI-ASL was used to evaluate 55 primary hypertension patients. There was no major variation between two consecutive mTI-ASL measurements in healthy volunteers. Furthermore, the rCBF and ATT values provided valuable information for the classification of hypertension, which can be used as a non-invasive quantitative monitoring MRI tool for hypertension progression.
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