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Abstract #1831

Quantitative measurement of cerebral blood flow in healthy volunteers and hypertension patients by multi-TI arterial spin labeling at 3 T MRI

Fan Qiuju1, Tan Hui1, Yang Zhen1, Yu Nan1, Yu Yong1, Wang Shaoyu2, Xue Yu3, and Li Yue3
1Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, China, 2MR senior scientific marketing specialist, Shaanxi, China, 3Shaanxi University of Chinese Medicine, Shaanxi, China

This study aimed to quantitative measurement of cerebral blood flow in different brain regions of different levels of blood pressure by mTI ASL. In the first part of this study, we evaluated the reproducibility of mTI-ASL in healthy subjects, and then mTI-ASL was used to evaluate 55 primary hypertension patients. There was no major variation between two consecutive mTI-ASL measurements in healthy volunteers. Furthermore, the rCBF and ATT values provided valuable information for the classification of hypertension, which can be used as a non-invasive quantitative monitoring MRI tool for hypertension progression.

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