The aetiopathogenesis of adolescent idiopathic scoliosis (AIS) remains elusive, with studies suggesting a neurological basis. Using a case control, multimodal approach incorporating volumetry and diffusion tensor imaging, we characterised brain MRI changes in AIS. The pontine volume was significantly larger while left insula was smaller in patients than controls. Whole brain Tract-Based Spatial Statistics (TBSS) showed no difference between subject cohorts. Tractography of the corticoreticular pathway (CRP), which innervates the axial muscles, showed significant differences in mean and axial diffusivity between the left and right CRP only in the patient cohort, but no such asymmetry in the control cohort.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords