Abstract #1839

MR radiomic features Correlate with EEG Connectivity during Intermittent Photic Stimulation in Patients with Cavernous Malformation

Nai-Chi Chen¹, Cheng-Chia Lee^2,3,4, Yo-Tsen Liu^3,5,6, Chien-Chen Chou², Chung-Jung Lin⁷, Wan-Yuo Guo^3,7, Wen-Yuh Chung^2,3, and Chia-Feng Lu¹

¹Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei City, Taiwan, ²Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan, ³School of Medicine, National Yang-Ming University, Taipei, Taiwan, ⁴Brain Research Center, National Yang-Ming University, Taipei, Taiwan, ⁵Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ⁶Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, ⁷Department of Radiology, Taipei Veteran General Hospital, Taipei, Taiwan

Cavernous malformation (CM) is one of the common cause for seizure attacks. Till now, the relationships between the structural characteristics of CM and the resultant abnormality of neural activity are still less explored. We employed MR radiomics analysis and EEG functional connectivity analysis to investigate whether quantitative and non-invasive features derived from these approaches can be used to differentiate CM patients with and without seizure. Furthermore, the association between structural and functional characteristics of CM were unraveled.

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