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Abstract #1839

MR radiomic features Correlate with EEG Connectivity during Intermittent Photic Stimulation in Patients with Cavernous Malformation

Nai-Chi Chen1, Cheng-Chia Lee2,3,4, Yo-Tsen Liu3,5,6, Chien-Chen Chou2, Chung-Jung Lin7, Wan-Yuo Guo3,7, Wen-Yuh Chung2,3, and Chia-Feng Lu1
1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei City, Taiwan, 2Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan, 3School of Medicine, National Yang-Ming University, Taipei, Taiwan, 4Brain Research Center, National Yang-Ming University, Taipei, Taiwan, 5Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 6Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, 7Department of Radiology, Taipei Veteran General Hospital, Taipei, Taiwan

Cavernous malformation (CM) is one of the common cause for seizure attacks. Till now, the relationships between the structural characteristics of CM and the resultant abnormality of neural activity are still less explored. We employed MR radiomics analysis and EEG functional connectivity analysis to investigate whether quantitative and non-invasive features derived from these approaches can be used to differentiate CM patients with and without seizure. Furthermore, the association between structural and functional characteristics of CM were unraveled.

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