Meeting Banner
Abstract #1981

Evaluating the Role of Bed Nucleus of Stria Terminalis in Anorexia Nervosa Restricting Type

Jianli Wang1, Lauren Spreen2, Xiaoyu Wang1, Christopher Freet3, Jeffrey Vesek2, Fauzia Mahr3, Lydia Petrovic-Dovat3, and Scott Bunce3
1Radiology, Penn State College of Medicine, Hershey, PA, United States, 2Molecular Biology, Penn State College of Medicine, Hershey, PA, United States, 3Psychiatry, Penn State College of Medicine, Hershey, PA, United States

There is growing evidence for the contribution of neurocircuitry regulating emotion, as well as appetite and body weight, in the etiology of anorexia nervosa (AN). The high prevalence of anxiety disorders in AN implicates a critical node in the neurocircuitry of anxiety. The bed nucleus of the stria terminalis (BNST) modulates not only responses to anxiogenic (versus fear) situations, but mediates anxious temperament and feeding as well, through efferent connections to the lateral hypothalamus. In this study, we sought to identify if there is significant functional and structural changes of BNST in AN related to food.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here