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Abstract #1982

Quantitative volumetric and parametric alterations in patients suffering from anorexia nervosa

Zaheer Abbas1, Syed Hammad Akhter1, Dominik Ridder1, and N. Jon Shah1,2,3
1Medical Imaging Physics, Institute of Neuroscience and Medicine 4, Jülich, Germany, 2Institute of Neuroscience and Medicine 11, INM 11, JARA, Jülich, Germany, 3Department of Neurology, Faculty of Medicine, Aachen, Germany

Anorexia nervosa (AN) is an eating disorder characterized by severe weight loss due to a fear of gaining weight and obsessions relating to body shape. AN is a psychiatric illness, and although psychiatric co-morbidity in AN has already been extensively studied, the extent to which it can affect mortality is unclear. In this work, a quantitative and volumetric study to monitor the disease-related integrity of the brain tissue in a cohort of AN patients and healthy controls was performed. The preliminary results suggest that psychological treatment may be useful in terms of brain tissue integrity, even after only three months.

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