Abstract #2003

The impact of B1+ inhomogeneities on automatic hippocampal morphometry using 7T MRI

Roy AM Haast¹, Jonathan C Lau^1,2, Dimo Ivanov³, Kamil Uludag^4,5, and Ali R Khan^1,6

¹Robarts Research Institute, Western University, London, ON, Canada, ²Department of Clinical Neurological Sciences, Division of Neurosurgery, Western University, London, ON, Canada, ³Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, ⁴Institute for Basic Science, Center for Neuroscience Imaging Research, Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea, ⁵University Health Network, Toronto, ON, Canada, ⁶Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada

We examined the effect of B₁⁺ inhomogeneities in 7T MP2RAGE data on hippocampal morphometry using volume- and surface-based evaluation methods. As for the cortex, significant variability in hippocampal and subcortical segmentation outputs are observed between original and corrected MP2RAGE data, especially near GM-CSF boundaries. Importantly, results of data acquired at two sites, using different MR hardware and sequence setups (B₁⁺-sensitive vs insensitive), become more comparable after B₁⁺ correction. These data emphasize the dependency of segmentation performances on anatomical image quality, and stresses the need for careful consideration of sequence parameters when setting up imaging protocols.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.