Meeting Banner
Abstract #2009

Dynamic response profiling of periaqueductal grey during a bladder filling protocol using 7T functional MRI

Job van den Hurk1,2, Mathijs de Rijk3, Sajjad M Rahnama'i3, and Gommert van Koeveringe4
1Scannexus Ultra-High Field MRI Center, Maastricht, Netherlands, 2Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 3Department of Urology, Maastricht University, Maastricht, Netherlands, 4Department of Urology, Maastricht University Medical Center (MUMC+), Maastricht, Netherlands

The periaqueductal grey (PAG) is a brainstem nucleus involved in storage and voiding of urine. We developed a novel method for creating dynamic response profiles for PAG, which requires three resting state ultra-high resolution fMRI datasets to be acquired: the first when the participant has an empty bladder, the second during filling of the bladder while subjective bladder sensations are recorded, and the third with a full bladder. PAG is functionally parcellated based on the full bladder scan, after which functional connectivity between the clusters is assessed for different states of bladder sensation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here