The combination of MR neurography (MRN) and comprehensive quantitative MRI is of great clinical significance for pathological analysis of peripheral nerves. This study aims to investigate simultaneous MRN, T2, T2* mapping of lumbar plexus by using a distortion-free multishot technique, Point-Spread-Function Encoded EPI (PSF-EPI). Particularly, the quantitative T2 and T2* mapping are conducted by using the multiple echo-shifted intermediate images of PSF-EPI. Also, PSF-EPI can be highly accelerated by the titled-CAIPI acquisition scheme. The acquisition time can be reduced to around 2 minutes. The efficacy of PSF-EPI is demonstrated on healthy volunteers and patients.
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